Friend or foe: the bifunctional role of steroid hormones in prostate cancer.

Androgen receptors in early and castration resistant prostate cancer: friend or foe?

Address for correspondence: Dr Marilena Kampa, University of Crete, School of Medicine, Laboratory of Experimental Endocrinology, P.O. Box 2208, Heraklion, 71110, Crete, Greece, Tel.: +3

Kant: Friend or Foe of the Believer? Plantinga and Other American Christian Responses to Kant's Epistemology

Association between the Asp327Asn Polymorphism of Sex Hormone-Binding Globulin Gene and Prostate Cancer

Background: By binding SHBG hormone to sex hormones, in addition to carrying them in the blood, they regulate the amount of tissue availability. Since the genetic changes in the structure of globulin affect it’s binding to hormones, so in this study the effects of single nucleotide change in exon 8 or rs 6259 in the incidence of prostate cancer is evaluated. Methods: The study populati...

بررسی نقش ژن CYP1B1 در سرطان پروستات در دو جمعیت ایرانی و هندی

 Prostate cancer (PCa) is the most common non-skin cancer and the second leading cause of cancer death among men in the world. Growth, maintenance and the expression of genes involved in the production of steroids, may alter the susceptibility of prostate cancer. One such gene, CYP1B1 (cytochrome P450, family 1, subfamily B, polypeptide 1) is involved in the activation of many carcinogens and i...

Apocrine Metaplasia in Intraductal Papilloma with Foci of DCIS: A Friend or Foe?

Malignant papillary neoplasms of the breast comprise a number of microscopically distinct lesions, where apocrine metaplasia is commonly found in papillomas compared to other papillary lesions including papillary carcinomas. However, association of apocrine metaplasia in papilloma with Ductal Carcinoma in Situ (DCIS) is not very well defined. The lesions with apocrine metaplasia are not only di...